VITAMIN B12 TASTE MASKING GRANULES
Cobalamin; Cyanocobalamin. Vitamin B12, also called cobalamin, is one of 8 B vitamins. All B vitamins help the body convert food (carbohydrates) into fuel (glucose), which is used to produce energy. Vitamin B12 is a soluble in water & solvents like ethanol & methanol. It is deep red colored crystals and it is stable at high temperatures. Vitamin B12 rapidly degrades in the presence of light and hence is kept in dark. Vitamin B12 can be obtained from liver & kidney of animals, milk & dairy products, Tuna etc. It is used to reduce inflammation, redness and to treat skin conditions like psoriasis & eczema.
PARTICLE SIZE
◉ Taste masked of Powder, Beads, Beadlets, Spheres, Granules, Pellets particle
◉ Size: 12/14#,14/18#,18/20#,16/20#,14/20#,20/30#,30/60#
◉ Aperture Micron: 1680-1410 µm, 1410-1000 µm,1000-841 µm,1190-841 µm,841-595 µm, 595-250 µm,250-75 µm
IUPAC NAME
◉ cobalt(3+);[(2R,3S,4R,5S)-5-(5,6-dimethylbenzimidazol-1-yl)-4-hydroxy-2-(hydroxymethyl)oxolan-3-yl] [(2R)-1-[3-[(1R,2R,3R,5Z,7S,10Z,12S,13S,15Z,17S,18S,19R)-2,13,18-tris(2-amino-2-oxoethyl)-7,12,17-tris(3-amino-3-oxopropyl)-3,5,8,8,13,15,18,19-octamethyl-
DRUG CLASSIFICATION
◉ B Vitamins; Vitamins, Water-Soluble
THERAPEUTIC ACTION
◉ vitamin B12 deficiency, cyanide poisoning, and high levels of homocysteine in the blood, used for canker sores, cataracts, Alzheimer disease, osteoporosis, fatigue, helps keep your body's blood and nerve cells healthy and helps make DNA, Nourishes the brain, Helps RBC’s formation, prevents anaemia, and prevents Osteoporosis
BENEFITS OF VITAMIN B12
- Adding a combination of sweeteners (sucralose, aspartame)
- Flavors (orange, mint) to mask the unpleasant taste of low to moderately bitter actives
- Taste masking increases drug acceptability and medication adherence in pediatric, geriatric, and other special patient populations
- Content uniformity with an excellent taste masking
- Reduce aversive sensory attributes
- To increases of bioavailability
- To alter drug release
- To produce a targeted drug delivery
- To decreases evaporation rate of core material
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