THYMOL TASTE MASKING GRANULES
Thymol, chemically known as 2-isopropyl-5-methylphenol is a colorless crystalline monoterpenes phenol. Thymol (2-isopropyl-5-methylphenol) is a white crystalline substance that gives thyme its strong flavor, pleasant aromatic odor and strong antiseptic property. Active ingredient used in food flavorings, topical ointments, various soaps, toothpastes, shampoos, deodorants and mouthwashes. Thymol is only slightly soluble in water at neutral pH, but it is extremely soluble in alcohols and other organic solvents. The major constituents of thyme are thymol, carvacrol, linalool, a-terpineol and 1, 8-cineole.
PARTICLE SIZE
◉ Taste masked of Powder, Beads, Beadlets, Spheres, Granules, Pellets particle
◉ Size: 12/14#,14/18#,18/20#,16/20#,14/20#,20/30#,30/60#
◉ Aperture Micron: 1680-1410 µm, 1410-1000 µm,1000-841 µm,1190-841 µm,841-595 µm, 595-250 µm,250-75 µm
IUPAC NAME
◉ 5-Methyl-2-(propan-2-yl) phenol
DRUG CLASSIFICATION
◉ phenols and a monoterpenoids
THERAPEUTIC ACTION
◉ improves digestion by relaxing smooth muscles, prevents menstrual cramps, attenuates respiratory problems, use as animal repellents, fungicides/fungistats, medical disinfectants, tuberculocides, and virucides, kills bacteria by disrupting the cell walls and cell membranes
BENEFITS OF THYMOL
- Adding a combination of sweeteners (sucralose, aspartame)
- Flavors (orange, mint) to mask the unpleasant taste of low to moderately bitter actives
- Taste masking increases drug acceptability and medication adherence in pediatric, geriatric, and other special patient populations
- Content uniformity with an excellent taste masking
- Reduce aversive sensory attributes
- To increases of bioavailability
- To alter drug release
- To produce a targeted drug delivery
- To decreases evaporation rate of core material
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