NIACINAMIDE TASTE MASKING GRANULES
Niacinamide is one form of vitamin B3 (niacin) that plays an important role in energy metabolism and cell health. It may offer benefits related to skin care and skin cancer, as well as chronic kidney disease and type 1 diabetes. Vitamin B3 plays a vital role in converting the food you eat food you into usable energy and helps your body's cells carry out important chemical reactions. It is a vitamin B3, a pyridinecarboxamide and a pyridine alkaloid. Niacinamide leads to an increase in protein synthesis (e.g. keratin), has a stimulating effect on ceramide synthesis, speeds up the differentiation of keratinocytes, and raises intracellular NADP levels. Niacinamide is non-acidic.
PARTICLE SIZE
◉ Taste masked of Powder, Beads, Beadlets, Spheres, Granules, Pellets particle
◉ Size: 12/14#,14/18#,18/20#,16/20#,14/20#,20/30#,30/60#
◉ Aperture Micron: 1680-1410 µm, 1410-1000 µm,1000-841 µm,1190-841 µm,841-595 µm, 595-250 µm,250-75 µm
IUPAC NAME
◉ pyridine-3-carboxamide
DRUG CLASSIFICATION
◉ Antilipemic Agents
THERAPEUTIC ACTION
◉ prevent vitamin B3 deficiency and related conditions such as pellagra, used for acne, diabetes, cancer, osteoarthritis, aging skin, skin discoloration, and many other conditions, moisturizing skin-care products, foods and supplements like multivitamins, helps hydrate skin, treats hyperpigmentation, promotes skin elasticity, decreases redness and blotchiness and acts as an antioxidant, fighting free radicals
BENEFITS OF NIACINAMIDE
- Adding a combination of sweeteners (sucralose, aspartame)
- Flavors (orange, mint) to mask the unpleasant taste of low to moderately bitter actives
- Taste masking increases drug acceptability and medication adherence in pediatric, geriatric, and other special patient populations
- Content uniformity with an excellent taste masking
- Reduce aversive sensory attributes
- To increases of bioavailability
- To alter drug release
- To produce a targeted drug delivery
- To decreases evaporation rate of core material
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