L-LEUCINE TASTE MASKING GRANULES
Leucine is one of the 3 essential branched chain amino acids (BCAAs). It is an essential amino acid, which means that humans cannot synthesize it. With a hydrocarbon side chain, leucine is classified as a hydrophobic amino acid. It has an isobutyl R group. It is used as a food additive, and is classified as a flavor enhancer. A branched-chain amino acid that consists of glycine in which one of the hydrogens attached to the α-carbon is substituted by an isobutyl group. Human dietary sources are foods that contain protein, such as meats, dairy products, soy products, and beans and other legumes.
PARTICLE SIZE
◉ Taste masked of Powder, Beads, Beadlets, Spheres, Granules, Pellets particle
◉ Size: 12/14#,14/18#,18/20#,16/20#,14/20#,20/30#,30/60#
◉ Aperture Micron: 1680-1410 µm, 1410-1000 µm,1000-841 µm,1190-841 µm,841-595 µm, 595-250 µm,250-75 µm
IUPAC NAME
◉ (2S)-2-amino-4-methylpentanoic acid
DRUG CLASSIFICATION
◉ Essential amino acid
THERAPEUTIC ACTION
◉ help in healing skin and bones, increase muscle growth and lean body mass, increase production of human growth hormone (HGH), help control blood sugar
BENEFITS OF L-LEUCINE
- Adding a combination of sweeteners (sucralose, aspartame)
- Flavors (orange, mint) to mask the unpleasant taste of low to moderately bitter actives
- Taste masking increases drug acceptability and medication adherence in pediatric, geriatric, and other special patient populations
- Content uniformity with an excellent taste masking
- Reduce aversive sensory attributes
- To increases of bioavailability
- To alter drug release
- To produce a targeted drug delivery
- To decreases evaporation rate of core material
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