DHA OIL TASTE MASKING GRANULES
A mixture of fish oil and primrose oil, doconexent is used as a high-docosahexaenoic acid (DHA) supplement. DHA is a 22 carbon chain with 6 cis double bonds with anti-inflammatory effects. It can be biosynthesized from alpha-linolenic acid or commercially manufactured from microalgae. It is an omega-3 fatty acid and primary structural component of the human brain, cerebral cortex, skin, and retina thus plays an important role in their development and function. Doconexent is a polyunsaturated very long-chain fatty acid with a 22-carbon backbone and 6 double bonds, originating from the 3rd, 6th, 9th, 12th, 15th and 18th positions from the methyl end. Docosahexaenoic acid (DHA) is an omega-3 fatty acid that is a primary structural component of the human brain, cerebral cortex, skin, and retina.
PARTICLE SIZE
◉ Taste masked of Powder, Beads, Beadlets, Spheres, Granules, Pellets particle
◉ Size: 12/14#,14/18#,18/20#,16/20#,14/20#,20/30#,30/60#
◉ Aperture Micron: 1680-1410 µm, 1410-1000 µm,1000-841 µm,1190-841 µm,841-595 µm, 595-250 µm,250-75 µm
IUPAC NAME
◉ (4Z,7Z,10Z,13Z,16Z,19Z)-Docosa-4,7,10,13,16,19-hexaenoic acid
DRUG CLASSIFICATION
◉ omega-3 fatty acid
THERAPEUTIC ACTION
◉ treatment for bipolar disorder, coronary heart disease, dysmenorrhea, hyperlipidemia, HTN, hypertriglyceridemia, Raynaud's syndrome, rheumatoid arthritis, stroke prevention, to decrease risk of prostate cancer (dietary fish), rheumatoid arthritis, psoriasis, and other chronic inflammatory conditions
BENEFITS OF DHA OIL
- Adding a combination of sweeteners (sucralose, aspartame)
- Flavors (orange, mint) to mask the unpleasant taste of low to moderately bitter actives
- Taste masking increases drug acceptability and medication adherence in pediatric, geriatric, and other special patient populations
- Content uniformity with an excellent taste masking
- Reduce aversive sensory attributes
- To increases of bioavailability
- To alter drug release
- To produce a targeted drug delivery
- To decreases evaporation rate of core material
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