CITRIC ACID TASTE MASKING GRANULES
Citric Acid is a weak acid with a chemical formula C6H8O7. It can occur in two forms - monohydrate or water-free (anhydrous). This acid is usually found in citrus fruits like lemons, oranges etc. It is considered as a tribasic acid. It is odourless, sour in taste, and appears as a white crystalline solid. It has a monoclinic crystal structure. This organic acid was isolated for the first time by chemist Carl Wilhelm Scheele in the year 1784. Since it is similar in resemblance to table salt, it is sold in the market as sour salt. Citric acid is an organic compound that is found in citrus fruits. It is a natural preservative and is also used in foods and soft drinks to imbue an acidic (or a sour) flavour.
PARTICLE SIZE
◉ Taste masked of Powder, Beads, Beadlets, Spheres, Granules, Pellets particle
◉ Size: 12/14#,14/18#,18/20#,16/20#,14/20#,20/30#,30/60#
◉ Aperture Micron: 1680-1410 µm, 1410-1000 µm,1000-841 µm,1190-841 µm,841-595 µm, 595-250 µm,250-75 µm
IUPAC NAME
◉ 2-hydroxypropane-1, 2, 3-tricarboxylic acid
DRUG CLASSIFICATION
◉ Organic compound, tricarboxylic acid
THERAPEUTIC ACTION
◉ helps prevent some kidney stones, used to treat metabolic acidosis, used to control pH, used as an alkalizing agent, buffering agent, emulsifier, sequestering agent, diuretic and expectorant, antioxidant, cleaning agent – as an ingredient in kitchen and bathroom cleaning solution, emulsifying agent in ice creams, add a sour taste to soft drinks and other food items, shampoo, used in sucrose crystallization in caramel, used in food colouring, used as a natural preservative
BENEFITS OF CITRIC ACID
- Adding a combination of sweeteners (sucralose, aspartame)
- Flavors (orange, mint) to mask the unpleasant taste of low to moderately bitter actives
- Taste masking increases drug acceptability and medication adherence in pediatric, geriatric, and other special patient populations
- Content uniformity with an excellent taste masking
- Reduce aversive sensory attributes
- To increases of bioavailability
- To alter drug release
- To produce a targeted drug delivery
- To decreases evaporation rate of core material
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