ASHWAGANDHA TASTE MASKING GRANULES
Withania somnifera, commonly known as Ashwagandha or winter cherry, is an evergreen shrub in the nightshade or solanaceae family that grows in India. Ashwagandha is perhaps best known for its ability to reduce stress. Withaferin A is a withanolide that has hydroxy groups replaced at positions 4 and 27 to form the 5, 6:22, 26-diepoxyergosta-2, 24-diene-1, 26-dione (the 4beta, 5beta, 6beta, 22R stereoisomer). It was isolated from Physalis longifolia and has cytotoxic properties. It functions as an apoptosis inducer and an anti-cancer agent. It is a 4-hydroxy steroid, a primary alcohol, an epoxy steroid, an enone, an ergostanoid, a secondary alcohol, a withanolide, and a 27-hydroxy steroid. it is believed to be useful as a medicinal herb in Ayurveda and is sold as a dietary supplement in many countries, there is insufficient scientific evidence to show that it is safe or effective in treating any disease
PARTICLE SIZE
◉ Taste masked of Powder, Beads, Beadlets, Spheres, Granules, Pellets particle
◉ Size: 12/14#,14/18#,18/20#,16/20#,14/20#,20/30#,30/60#
◉ Aperture Micron: 1680-1410 µm, 1410-1000 µm,1000-841 µm,1190-841 µm,841-595 µm, 595-250 µm,250-75 µm
IUPAC NAME
◉ (1S,2R,6S,7R,9R,11S,12S,15R,16S)-6-hydroxy-15-[(1S)-1-[(2R)-5-(hydroxymethyl)-4-methyl-6-oxo-2,3-dihydropyran-2-yl]ethyl]-2,16-dimethyl-8-oxapentacyclo[9.7.0.02,7.07,9.012,16]octadec-4-en-3-one
DRUG CLASSIFICATION
◉ Adaptogen
THERAPEUTIC ACTION
◉ Levels of testosterone significantly, improve sexual desire, pleasure, and improved erections, Relieves stress and anxiety, lowers blood sugar and fat, increases muscle and strength, sharpens focus and memory, and supports heart health
BENEFITS OF ASHWAGANDHA
- Adding a combination of sweeteners (sucralose, aspartame)
- Flavors (orange, mint) to mask the unpleasant taste of low to moderately bitter actives
- Taste masking increases drug acceptability and medication adherence in pediatric, geriatric, and other special patient populations
- Content uniformity with an excellent taste masking
- Reduce aversive sensory attributes
- To increases of bioavailability
- To alter drug release
- To produce a targeted drug delivery
- To decreases evaporation rate of core material
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