BITTER GOURD

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BITTER GOURD TASTE MASKING GRANULES

Bitter gourd (Momordica charantia) is an important vegetable crop and is grown for its immature tuberculate fruits which have a unique bitter taste. Momordicine is an alkaloid and is also an important part of the chemical makeup of the bitter gourd because this is the chemical responsible for the bitterness of the vegetable. It has many other important chemicals such as the glycoproteins alpha-momorcharin and beta-momorcharin. The main constituents of bitter melon (Karela) are triterpene, protein, steroid, alkaloid, inorganic, lipid, and phenolic compounds .Momordica charantia (Karela) consists the following chemical constituents those are alkaloids, momordicin and charantin.

PARTICLE SIZE

◉ Taste masked of Powder, Beads, Beadlets, Spheres, Granules, Pellets particle

◉ Size: 12/14#,14/18#,18/20#,16/20#,14/20#,20/30#,30/60#

◉ Aperture Micron: 1680-1410 µm, 1410-1000 µm,1000-841 µm,1190-841 µm,841-595 µm, 595-250 µm,250-75 µm

IUPAC NAME

Momordica charantia Mizo

DRUG CLASSIFICATION

Magnoliopsida

THERAPEUTIC ACTION

reduces ageing and fights acne and skin blemishes, useful in treating various skin infections like ringworm, psoriasis, and itching, improves appetite, serves as a laxative, antibilious, emetic in cases of stomach wash, antiparasitic and is also recommended for treating cough, respiratory ailments and for managing rheumatism.

BENEFITS OF BITTER GOURD

  • Adding a combination of sweeteners (sucralose, aspartame)
  • Flavors (orange, mint) to mask the unpleasant taste of low to moderately bitter actives
  • Taste masking increases drug acceptability and medication adherence in pediatric, geriatric, and other special patient populations
  • Content uniformity with an excellent taste masking
  • Reduce aversive sensory attributes
  • To increases of bioavailability
  • To alter drug release
  • To produce a targeted drug delivery
  • To decreases evaporation rate of core material

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